{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# 2. Train U-Net\n",
    "\n",
    "## Summary\n",
    "\n",
    "* split images and masks to train and test sets of 80:20 ratio\n",
    "* load unet and train\n",
    "* calculate sensitivty for predicted masks that have at least 5 pixel overlap with the ground truth mask"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "import numpy as np\n",
    "\n",
    "#EDIT HERE##############################\n",
    "datafolder='processeddata'\n",
    "weightsfolder='modelweights'\n",
    "noduleimages=np.load(datafolder+\"/noduleimages.npy\")\n",
    "nodulemasks=np.load(datafolder+\"/nodulemasks.npy\")\n",
    "\n",
    "########################################\n",
    "\n",
    "\n",
    "from glob import glob\n",
    "import matplotlib.pyplot as plt\n",
    "import os\n",
    "from keras.models import Sequential,load_model,Model\n",
    "from keras.layers import Dense, Dropout, Activation, Flatten\n",
    "from keras.layers import Conv2D, MaxPooling2D, SpatialDropout2D\n",
    "from keras.layers import Input, merge, UpSampling2D, BatchNormalization\n",
    "from keras.optimizers import Adam\n",
    "from keras.preprocessing.image import ImageDataGenerator\n",
    "from keras.callbacks import EarlyStopping, ModelCheckpoint\n",
    "from keras import backend as K\n",
    "import pandas as pd\n",
    "from keras.callbacks import ModelCheckpoint\n",
    "import h5py\n",
    "from sklearn.model_selection import train_test_split\n",
    "from sklearn.metrics import roc_curve, auc\n",
    "\n",
    "K.set_image_dim_ordering('th') "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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70uI338cgllfV4236CWB5m74QeGxoucOtTZI0JmM7SF1VBdRs10uyOcmeJHuOHz/eQ2WS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\nJEmdDAhJUicDQpLUyYCQJHX6/5qX1XsqupFoAAAAAElFTkSuQmCC\n",
      "text/plain": [
       "<matplotlib.figure.Figure at 0x525d198>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "nodulesize=[np.sum(mask) for mask in nodulemasks]\n",
    "plt.hist([nod for nod in nodulesize if nod<300],bins=50)\n",
    "plt.xlabel(\"Area\")\n",
    "plt.ylabel(\"frequency\")\n",
    "plt.show()\n",
    "#remove samples with nodulesize<25, which is ~radius=2.8\n",
    "#filteredindicies=[i for i in range(len(nodulesize)) if nodulesize[i]>25]\n",
    "#noduleimages=noduleimages[filteredindicies]\n",
    "#nodulemasks=nodulemasks[filteredindicies]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "noduleimages=noduleimages.reshape(noduleimages.shape[0],1,512,512)\n",
    "nodulemasks=nodulemasks.reshape(nodulemasks.shape[0],1,512,512)\n",
    "imagestrain, imagestest, maskstrain, maskstest = train_test_split(noduleimages,nodulemasks,test_size=.20)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "#Code sourced from https://www.kaggle.com/c/data-science-bowl-2017#tutorial\n",
    "smooth = 1.0\n",
    "width = 32\n",
    "\n",
    "def dice_coef(y_true, y_pred):\n",
    "    y_true_f = K.flatten(y_true)\n",
    "    y_pred_f = K.flatten(y_pred)\n",
    "    intersection = K.sum(y_true_f * y_pred_f)\n",
    "    return (2. * intersection + smooth) / (K.sum(y_true_f) + K.sum(y_pred_f) + smooth)\n",
    "def dice_coef_loss(y_true, y_pred):\n",
    "    return -dice_coef(y_true, y_pred)\n",
    "\n",
    "def unet_model():\n",
    "    inputs = Input((1,512, 512))\n",
    "    conv1 = Conv2D(width, 3, 3, activation='relu', border_mode='same')(inputs)\n",
    "    conv1 = BatchNormalization(axis = 1)(conv1)\n",
    "    conv1 = Conv2D(width, 3, 3, activation='relu', border_mode='same')(conv1)\n",
    "    pool1 = MaxPooling2D(pool_size=(2, 2))(conv1)\n",
    "\n",
    "    conv2 = Conv2D(width*2, 3, 3, activation='relu', border_mode='same')(pool1)\n",
    "    conv2 = BatchNormalization(axis = 1)(conv2)\n",
    "    conv2 = Conv2D(width*2, 3, 3, activation='relu', border_mode='same')(conv2)\n",
    "    pool2 = MaxPooling2D(pool_size=(2, 2))(conv2)\n",
    "\n",
    "    conv3 = Conv2D(width*4, 3, 3, activation='relu', border_mode='same')(pool2)\n",
    "    conv3 = BatchNormalization(axis = 1)(conv3)\n",
    "    conv3 = Conv2D(width*4, 3, 3, activation='relu', border_mode='same')(conv3)\n",
    "    pool3 = MaxPooling2D(pool_size=(2, 2))(conv3)\n",
    "\n",
    "    conv4 = Conv2D(width*8, 3, 3, activation='relu', border_mode='same')(pool3)\n",
    "    conv4 = BatchNormalization(axis = 1)(conv4)\n",
    "    conv4 = Conv2D(width*8, 3, 3, activation='relu', border_mode='same')(conv4)\n",
    "    pool4 = MaxPooling2D(pool_size=(2, 2))(conv4)\n",
    "\n",
    "    conv5 = Conv2D(width*16, 3, 3, activation='relu', border_mode='same')(pool4)\n",
    "    conv5 = BatchNormalization(axis = 1)(conv5)\n",
    "    conv5 = Conv2D(width*16, 3, 3, activation='relu', border_mode='same')(conv5)\n",
    "\n",
    "    up6 = merge([UpSampling2D(size=(2, 2))(conv5), conv4], mode='concat', concat_axis=1)\n",
    "    conv6 = SpatialDropout2D(0.35)(up6)\n",
    "    conv6 = Conv2D(width*8, 3, 3, activation='relu', border_mode='same')(conv6)\n",
    "    conv6 = Conv2D(width*8, 3, 3, activation='relu', border_mode='same')(conv6)\n",
    "\n",
    "    up7 = merge([UpSampling2D(size=(2, 2))(conv6), conv3], mode='concat', concat_axis=1)\n",
    "    conv7 = SpatialDropout2D(0.35)(up7)\n",
    "    conv7 = Conv2D(width*4, 3, 3, activation='relu', border_mode='same')(conv7)\n",
    "    conv7 = Conv2D(width*4, 3, 3, activation='relu', border_mode='same')(conv7)\n",
    "\n",
    "    up8 = merge([UpSampling2D(size=(2, 2))(conv7), conv2], mode='concat', concat_axis=1)\n",
    "    conv8 = SpatialDropout2D(0.35)(up8)\n",
    "    conv8 = Conv2D(width*2, 3, 3, activation='relu', border_mode='same')(conv8)\n",
    "    conv8 = Conv2D(width*2, 3, 3, activation='relu', border_mode='same')(conv8)\n",
    "\n",
    "    up9 = merge([UpSampling2D(size=(2, 2))(conv8), conv1], mode='concat', concat_axis=1)\n",
    "    conv9 = SpatialDropout2D(0.35)(up9)\n",
    "    conv9 = Conv2D(width, 3, 3, activation='relu', border_mode='same')(conv9)\n",
    "    conv9 = Conv2D(width, 3, 3, activation='relu', border_mode='same')(conv9)\n",
    "    conv10 = Conv2D(1, 1, 1, activation='sigmoid')(conv9)\n",
    "\n",
    "    model = Model(input=inputs, output=conv10)\n",
    "    model.compile(optimizer=Adam(lr=1e-5), loss=dice_coef_loss, metrics=[dice_coef])\n",
    "    return model"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:15: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(32, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "  from ipykernel import kernelapp as app\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:17: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(32, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:20: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(64, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:22: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(64, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:25: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(128, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:27: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(128, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:30: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(256, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:32: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(256, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:35: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(512, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:37: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(512, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:39: UserWarning: The `merge` function is deprecated and will be removed after 08/2017. Use instead layers from `keras.layers.merge`, e.g. `add`, `concatenate`, etc.\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\keras\\legacy\\layers.py:458: UserWarning: The `Merge` layer is deprecated and will be removed after 08/2017. Use instead layers from `keras.layers.merge`, e.g. `add`, `concatenate`, etc.\n",
      "  name=name)\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:41: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(256, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:42: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(256, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:44: UserWarning: The `merge` function is deprecated and will be removed after 08/2017. Use instead layers from `keras.layers.merge`, e.g. `add`, `concatenate`, etc.\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:46: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(128, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:47: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(128, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:49: UserWarning: The `merge` function is deprecated and will be removed after 08/2017. Use instead layers from `keras.layers.merge`, e.g. `add`, `concatenate`, etc.\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:51: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(64, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:52: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(64, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:54: UserWarning: The `merge` function is deprecated and will be removed after 08/2017. Use instead layers from `keras.layers.merge`, e.g. `add`, `concatenate`, etc.\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:56: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(32, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:57: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(32, (3, 3), activation=\"relu\", padding=\"same\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:58: UserWarning: Update your `Conv2D` call to the Keras 2 API: `Conv2D(1, (1, 1), activation=\"sigmoid\")`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:60: UserWarning: Update your `Model` call to the Keras 2 API: `Model(inputs=Tensor(\"in..., outputs=Tensor(\"co...)`\n",
      "c:\\programdata\\anaconda3\\envs\\tensorflow\\lib\\site-packages\\ipykernel_launcher.py:8: UserWarning: The `nb_epoch` argument in `fit` has been renamed `epochs`.\n",
      "  \n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Train on 4018 samples, validate on 1005 samples\n",
      "Epoch 1/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.0830 - dice_coef: 0.0830Epoch 00000: loss improved from inf to -0.08300, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 598s - loss: -0.0830 - dice_coef: 0.0830 - val_loss: -0.2151 - val_dice_coef: 0.2151\n",
      "Epoch 2/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.2625 - dice_coef: 0.2625Epoch 00001: loss improved from -0.08300 to -0.26267, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 582s - loss: -0.2627 - dice_coef: 0.2627 - val_loss: -0.3493 - val_dice_coef: 0.3493\n",
      "Epoch 3/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.3636 - dice_coef: 0.3636Epoch 00002: loss improved from -0.26267 to -0.36339, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 581s - loss: -0.3634 - dice_coef: 0.3634 - val_loss: -0.4280 - val_dice_coef: 0.4280\n",
      "Epoch 4/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.4369 - dice_coef: 0.4369Epoch 00003: loss improved from -0.36339 to -0.43692, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 582s - loss: -0.4369 - dice_coef: 0.4369 - val_loss: -0.4941 - val_dice_coef: 0.4941\n",
      "Epoch 5/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.4770 - dice_coef: 0.4770Epoch 00004: loss improved from -0.43692 to -0.47681, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 577s - loss: -0.4768 - dice_coef: 0.4768 - val_loss: -0.4864 - val_dice_coef: 0.4864\n",
      "Epoch 6/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.5088 - dice_coef: 0.5088Epoch 00005: loss improved from -0.47681 to -0.50888, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 576s - loss: -0.5089 - dice_coef: 0.5089 - val_loss: -0.5356 - val_dice_coef: 0.5356\n",
      "Epoch 7/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.5344 - dice_coef: 0.5344Epoch 00006: loss improved from -0.50888 to -0.53452, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 569s - loss: -0.5345 - dice_coef: 0.5345 - val_loss: -0.5137 - val_dice_coef: 0.5137\n",
      "Epoch 8/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.5565 - dice_coef: 0.5565Epoch 00007: loss improved from -0.53452 to -0.55627, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 569s - loss: -0.5563 - dice_coef: 0.5563 - val_loss: -0.5298 - val_dice_coef: 0.5298\n",
      "Epoch 9/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.5755 - dice_coef: 0.5755Epoch 00008: loss improved from -0.55627 to -0.57560, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 571s - loss: -0.5756 - dice_coef: 0.5756 - val_loss: -0.5490 - val_dice_coef: 0.5490\n",
      "Epoch 10/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6032 - dice_coef: 0.6032Epoch 00009: loss improved from -0.57560 to -0.60339, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 572s - loss: -0.6034 - dice_coef: 0.6034 - val_loss: -0.5534 - val_dice_coef: 0.5534\n",
      "Epoch 11/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.5986 - dice_coef: 0.5986Epoch 00010: loss did not improve\n",
      "4018/4018 [==============================] - 570s - loss: -0.5987 - dice_coef: 0.5987 - val_loss: -0.5761 - val_dice_coef: 0.5761\n",
      "Epoch 12/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6252 - dice_coef: 0.6252Epoch 00011: loss improved from -0.60339 to -0.62536, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6254 - dice_coef: 0.6254 - val_loss: -0.5801 - val_dice_coef: 0.5801\n",
      "Epoch 13/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6356 - dice_coef: 0.6356Epoch 00012: loss improved from -0.62536 to -0.63573, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6357 - dice_coef: 0.6357 - val_loss: -0.5994 - val_dice_coef: 0.5994\n",
      "Epoch 14/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6435 - dice_coef: 0.6435Epoch 00013: loss improved from -0.63573 to -0.64358, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6436 - dice_coef: 0.6436 - val_loss: -0.5874 - val_dice_coef: 0.5874\n",
      "Epoch 15/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6661 - dice_coef: 0.6661Epoch 00014: loss improved from -0.64358 to -0.66612, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6661 - dice_coef: 0.6661 - val_loss: -0.5948 - val_dice_coef: 0.5948\n",
      "Epoch 16/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6692 - dice_coef: 0.6692Epoch 00015: loss improved from -0.66612 to -0.66922, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6692 - dice_coef: 0.6692 - val_loss: -0.5647 - val_dice_coef: 0.5647\n",
      "Epoch 17/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6754 - dice_coef: 0.6754Epoch 00016: loss improved from -0.66922 to -0.67552, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6755 - dice_coef: 0.6755 - val_loss: -0.5754 - val_dice_coef: 0.5754\n",
      "Epoch 18/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6745 - dice_coef: 0.6745Epoch 00017: loss did not improve\n",
      "4018/4018 [==============================] - 566s - loss: -0.6745 - dice_coef: 0.6745 - val_loss: -0.5871 - val_dice_coef: 0.5871\n",
      "Epoch 19/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6880 - dice_coef: 0.6880Epoch 00018: loss improved from -0.67552 to -0.68816, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6882 - dice_coef: 0.6882 - val_loss: -0.6117 - val_dice_coef: 0.6117\n",
      "Epoch 20/20\n",
      "4016/4018 [============================>.] - ETA: 0s - loss: -0.6902 - dice_coef: 0.6902Epoch 00019: loss improved from -0.68816 to -0.69033, saving model to unet-weights-improvement2.hdf5\n",
      "4018/4018 [==============================] - 566s - loss: -0.6903 - dice_coef: 0.6903 - val_loss: -0.6152 - val_dice_coef: 0.6152\n"
     ]
    }
   ],
   "source": [
    "# Train model on dataset with only nodules\n",
    "model=unet_model()\n",
    "filepath=weightsfolder+\"/unet-weights-improvement.hdf5\"\n",
    "#model.load_weights(filepath)\n",
    "\n",
    "checkpoint = ModelCheckpoint(filepath, monitor='loss', verbose=1, save_best_only=True)\n",
    "history=model.fit(imagestrain, maskstrain, batch_size=4, nb_epoch=20, verbose=1, shuffle=True,\n",
    "              callbacks=[checkpoint],validation_data=(imagestest,maskstest))\n",
    "#history=model.fit_generator(generator(batch_size=batchsize), steps_per_epoch=len(nonzeroindex)/batchsize-batchsize*11, nb_epoch=1, callbacks=callbacks_list)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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BitIUFZYUjN/MmePcPP79d2e5Rg149FEnIWSWmOxcJUSHR3P0X0fzPTxzUkoS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\nw/8D9e5QsuRMNlUAAAAASUVORK5CYII=\n",
      "text/plain": [
       "<matplotlib.figure.Figure at 0x36b278710>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "plt.plot(history.history['dice_coef'], color='b')\n",
    "plt.plot(history.history['val_dice_coef'], color='g')\n",
    "plt.xlabel(\"Epoch\")\n",
    "plt.ylabel(\"Dice Coefficient\")\n",
    "plt.legend([\"Train\", \"Validation\"])\n",
    "plt.show()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "1004/1005 [============================>.] - ETA: 0s"
     ]
    },
    {
     "data": {
      "text/plain": [
       "[-0.67809058924145371, 0.67809058924145371]"
      ]
     },
     "execution_count": 8,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "model.evaluate(imagestest,maskstest, batch_size=4)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 31,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "0.6069651741293532"
      ]
     },
     "execution_count": 31,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "num_test=imagestest.shape[0]\n",
    "imgs_mask_test = np.ndarray([num_test,1,512,512],dtype=np.float32)\n",
    "for i in range(num_test):\n",
    "    imgs_mask_test[i] = model.predict([imagestest[i:i+1]], verbose=0)[0]\n",
    "\n",
    "sumoverlap=[]\n",
    "for i in range(num_test):\n",
    "    sumoverlap.append(np.sum(maskstest[i,0]*imgs_mask_test[i,0]))\n",
    "\n",
    "#nodulemasks\n",
    "len([ov for ov in sumoverlap if ov>1])/len(sumoverlap)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 32,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Predicted\n"
     ]
    },
    {
     "data": {
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      "text/plain": [
       "<matplotlib.figure.Figure at 0x12df40ba8>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Ground Truth\n"
     ]
    },
    {
     "data": {
      "image/png": "iVBORw0KGgoAAAANSUhEUgAAAQYAAAD8CAYAAACVSwr3AAAABHNCSVQICAgIfAhkiAAAAAlwSFlz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\nSR3DIKljGCR1DIOkjmGQ1PlfqZJy6H2ax1kAAAAASUVORK5CYII=\n",
      "text/plain": [
       "<matplotlib.figure.Figure at 0x132f6b128>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Image\n"
     ]
    },
    {
     "data": {
      "image/png": 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v9rgD4zkIzJ2zoOj999/H1NSUFP4wRuXk4QKjRp+tyEOhkLR0Y9qQO73urKQ9\nB07MeDyOaDSKfD4vaUGWKDONyJw7vRY2PeHv9A4ACDMfDAaxvLxsy8/H43H09PRgz549thh5s0uG\nX3zxRWmFxz6We/bsAQC8+eabNrk43W5ec29vL7q7u3H58mXk83kRKhEkCJRcjOQI+BymmTuVjAyz\nisWidLTSiktNNDIs1OFfOBy2VZDSq9OeDjUOv/71r/Hwww+jv79fvE2C1L1m29pj4A7FDES9XsfM\nzAyuXr0qRU7cyen6s0lHX18fksmkpC6z2ax0LGbrdp3vZ8yay+UkdcjPB1q7/gMPPCALhuk0LnR6\nLZzgmrGnhoJhBP9O4OhUU9brdfT29krs7Xa7t+w4OwIid3j2oIxEIpLyq1QqIrxi85l0Oo2enh4k\nEgkpO6dnodWN9IgYXmlVJO+n9rbIIdDro7egeSLWh2iPkICvPTU99gQHhhf1eh1zc3O4cuWKLZPk\n8/lw//33b8nYfxHbth7D+Pi43Dye6HT79m189NFHsntwwcViMZu+gMrDTCaDbDZrIwoZz9L9J9+g\nU1q6+xK9CbZAZx8EvQvRO+EkYxWirgTk4icpB7SUi1z4nIRAK1yKxWLiSm/lrvXSSy/h1KlTtsrI\neDyOvXv34tKlS0Kgcvx55FypVMK5c+eEgNXaAwC2lKXW2GhXX48TQRNoido66z/q9bpNeMaaB00M\nE4h1WlkXmOkSc4LFtWvX0NPTI2DwSRL5e8G2LTAAkPid+vh3330XU1NTQsJxdykUCsJQu1wuKXAi\ncABtchKAaOSDwSBSqZSIlLizcRID7XRZuVzGhx9+KCXHzBrwMwYHB209IVnqTYadE7RYLEroAbQn\nOD0Mnvq0srIi3ai3un/Ayy+/jJMnT9oW0YMPPoh6vY7JyUkAEE6FAFKtVjE9PW0DSC56LVnWOo+u\nri6srKx8YuEUx5jVqfSkNMHJzyJgE1h5P0lsMqwgyBKI2XyWXggB7Y033sDAwABSqZSkvx977DG8\n8cYbW3of/jPblqHE+Pj4OllysVjE3NycEFTsSMzTniir1S3GCAA6FcgJQo0/1ZI8AYkHrVBXoJWK\nuVxO4mWCESdaIpGQiUXVIr0DCngIZsxK6NQbvyPl3jpb4na75Vi4rbJXXnlFFjY9nJ07dyISiaBW\nq6FYLAq4EcC1wpNpTIIaQ0JNCOqScv6dXBIBhZ4XiU2OCb0EenIAJIzrJDn5HTqVp6urqwLmvC5j\nDEqlEj5TZaXwAAAgAElEQVT66CPhkPiahx9+eEvvwX9m29Jj0IIZToZbt24hnU5L2lDfeMqcuROx\nFBpoN3olB8DdhRNLS3FJLHJnIs9Ad5XXxipBCpHi8bi0Duss4NHsPOsuGH8XCgUBCTZ84XPn5+eF\nXO3sCrVVxl2c5F4sFsPQ0BAWFxdtSkaCgq405YLkeGmBE9BOVWpFKu81Fyifx78TWEkcc/MgUPM+\nka/p9BZ5X1i/ArQ7XtHrISjduHED3d3d0viGm9G9YtvOY2B5t04HLiwsSKMRZhjIZDNfzQmixUgk\nq7TIiAtek1KVSgU3b96UXgN0/5mvZzaBp1tTj0DR0crKCqanp2XB04XlDsrHyuWyeAUrKyuyMDgZ\nucgAyCE4/GyfzycZg62yX/3qVzIG4XAYkUgE4+PjiMVi8Hq9SCaTNq4BaCsd6QkRxPWJXDrt2Nvb\nKxkOhltUYxLsec/5ehq9Ep0d4r2jF8FQg/0rWKmqa220IpbXsLS0hHfeeUe6WxHctvoefJptO49B\n1/NzwczMzGB5eRlAm6UGYMtP8+ayVwF3ft7QzhoG7kB8Pw0m9CL4niQhqewjWGhBkH6NJue4qLQ8\nl56Gy+UScCNhGovFxLtYXFyU5zHm3mrTY0yyL5lMYnV1VVSLsVgMHo8HKysr4uazpoWpWi2IYlET\nMwGaPyAw65CE/A8BsjMsY9hFL0YL26hvACD3njwS0PYASZZqsjGXy+HKlSu2lvx34x58kt0bV7GF\nxonBhba8vIy3335bjmrTOxInysjICPr7+yVjQBeWYMCUGL2GTxLf8O/kK5g6i8ViiMfjNtGU7iuo\nW6OzbbrW++uQg4QlCTVyIPpEqnQ6LR2hb926hcuXL0socTdy6i+99JIAKNBaXA888AD6+/ulo1Im\nk5FuSFQ8ArCpC/VhOdqDoqqSY0YQJBnIe8N7qk/Y1pqEaDSK7u5uyVCRVCQpyVBS6x10kRg9R30Q\nDoVPt2/flvtcr9fxxBNPbPl96LRtBQwPPvigraag0WgI4ciFzoNNQ6GQnAANAIVCQSYUAHHNuRj1\nBOAuoXPnnMDMHLB/IzMirHBkPMrdKp/P25q98to1eUhXV3eJonehwx89efm8ixcvSjx8N8vfCape\nr1dO69bjAUBUk5SF87oJppRTa2KWZfK6VoVcBF17krnGGNGfkCdiCDE6Ooonn3wSO3fuBACpniWI\n8H5pkpH3EYDNa+T3Jf9w48YNW/VrZ9u/u2HbChiAdnqQdQ/Xrl0TlNeTjghfLBYxPz+PTCZjc/85\nqbjIuGvQrdRNQ1kFqQU33KXz+TyKxaIIoLircKFQ7agzHgS3aDSKaDRqK6rSBBi/UyQSEcKMC42Z\nicXFRczMzNjqBrbaXnrpJQFWjmVPT4/s8gRC1qLoTAsrN3XBGceY94k6AoqVtLza7W711NBAzr6R\nDAM9ntZ5n9PT0xJyMvzg3CGJykwI5xi7U2mvqLOfw/Xr17G4uAifzyf8x922bcUxMDQAWhNoZWUF\nMzMz4kbqOJATjIufyK/dbu48LJXmDs0FzInN1+kdS7dCZ/zLiZlOpwUsNH/B15IAKxaLiMViCAQC\n4oHwmphN4a7JLtXMjnBXZAVgf38/KpUKHnroIQERY4zUdmjl5Kuvvrrh94bfgdc+ODiIYDAoJdbc\n+V2u1sEwhUIB0WhUMj8kLAOBgIA4PQiGidSF8JwPenb6XjebTQEf9oVsNBpS7MUQTnMIbHfHMaI3\nEAwGMTo6io8++kjAgCEf5wTv9+TkJEZHRzE8PIxCoYDf//3fx7/+679+8mBtgW0bj2H//v2C7AAk\njNDoDbQ9is4iHJYBA20pdafQRu8I5Bk4YciCkzU/ceIEgHZVnjEGjz76KI4dO2Zze4G2qk+nKkli\nra6uAoDwGfysaDQq155MJrF3715pOacFV/z+9FR0rQG9Cn5vAuATTzyx4ew5U3XkR6LRKAYHB20E\nbrFYxOrqqpC0OlPEMWG4xbCJ4AtA+Bi/34/u7m4Zex1iGdNqgad7YWpvjc8nH8DsEsvttWCtVCoh\nm81KqpjAQB6K38vtdmN5eVk6Tmku4m7ZtgEGNmPlZCBK88bTdeTi4mTQpCJ3Y+62nATcqeiO6p+Z\nYmR4wMn11ltvSZ0FvZCxsTHpEUmPg9eg+QJeC3sXMOTg3+v1Ou677z5pK1etVqVJaTqdtoEUFyF3\nOqZLdd0Bz3XIZrMoFovimm8kOPziF7+QmJ3349ChQ7Zj9jprEUqlklwPtSLpdFoyRgBs4MCx51kd\nfB4XKUM2hpM61ahFURwbepaslCVpTMCgaE4Dhr5H/B71eh1LS0uYnJyU78Xs192ybRNKsJU4UfrG\njRtYXV0V90+fwtxoNEQ/z9QUJ5VWGfJnhh8kwZgTB1og0t3djWw2K94CP4ctxlmY85Of/EROfuJE\n1IVSBK5msymnSrndbsTj8XUew/79+zEyMoJXXnnFJgtmkRb5kKGhIRw6dEhOx+L4+Hw+EVZxEieT\nSQCQzIDP58PTTz+9Yf0bdFqRwEfeR5dlc6FznHQKkB4P3wNoVWqyjXutVsPCwgLm5+dRr9dFw8B7\nTk+NgE/ZdKFQEEWmJhKZ3SCo6JJxoOVd8lQseizBYBCxWEy8DFb1Xrt2DYVCAb29vZibm8NTTz11\n106y2jbAoKWzzWYTS0tL6zQG+jh4HavztdxNuFswTtW/082kWpKvo36A8WdfXx98Pp/0kyR3wB2K\nIidOVL4nr1V3V9ZGpWQikZCWdD6fDw8++CDeffddyVzwWhqNBt566y2MjY1JXUdXV+vsoJs3b+Ls\n2bOoVqtIJBI4cOAARkdHEYvFbC3nN8qef/55nD592rZDezweZLNZ0XoQEOlqExyBNv+iS6vpzfHe\ncrfW3gAfozZCd9vW2pVO8laL2RjCEKT4HQgAzDpx3CKRCEKhkDTnIf/z8ccf48SJEwgEAnf1sJpt\nAQxPPvmkuHDM7S8sLMjuwknB2Js7KheO5iWI8JyETGHSpefN5/8ARFLLhd/X14fBwUFRJ+rdjkAU\ni8UkDcr6DbqeJLsYVujKT+6kH3zwgZy+7fV68f7779sYeT53cXFRdt7+/n5YloXV1VWcO3cO586d\nw6FDh/D+++8DaLWFf/zxx/Hwww/b2sVtpPEesNdBNBoV3QXrDhgW8roJDhQ81eut/hb0gjh+BJDO\ncIHSca/Xi+7ubiwvL6/TG/A1OvtEoGJIoQlinflh1kTzUvrkLN6ParWKDz74AHv37gXQ8lpOnz59\nV07O3hbAAMC2qPSN13l/3ReQrih3Hl07QV27rsbjZzCPrpVzuk1bs9nE1NQU5ubmRO3HI9s4ebm4\nuRvr3oe8DpKaDB34P0+hmp+fl/dgxySmRH0+H2KxGCzLkvqL+fl5qfN46aWX8Jvf/AaWZeGNN96Q\nEKhUKuH555/H/Pw8fu/3fg9ut1u0BBtl/M7c1WOxmIRCuq7DsiwEAgGpbdCaA0qk+R5UfzKU6uvr\nQ7VaxcrKinwW58Di4qJN+UjRFCtRWRynS7npNdDL5D2qVqtyvgSFcRrIOR8JUh6PBx988AFGR0cx\nPj4u+oq7YduCfNQ5be4QjKepNyB51Cmp5UTlzkNhTSaTEdeSNxuATCS+j3aJ+T89EZJ8FMskk0mZ\n0PpQFJ1N0dWAXAg+nw+JREJcW75WE3Y6bNJdqfj5BEqv14tr167ZJqQWVjWbTdy8eRPZbFa8jlOn\nTm3YvXrhhRdsVZXBYBC5XA5LS0uSps3n8xKvP/7449i1axdisRgGBgawa9cuDAwMSLMXjhfJ5Eaj\ngZmZGdy6dUuyMMw48N6Si+L4MjwgAax5CaateR90VksrXvk59CTorTIc5TXk83lMTk4Kh3O3bFt4\nDLxputswb75WJXKR9PT0SF8GTgoSbgQKLkIy0ryJJDnpPdC9JEhwsnBScrfzeDxS7ENyUmv5AYjr\nCrQXNBcty8D5N33wDY9lc7lcCAQCQioyL8/vR3c2m83K2D322GMAYOsVwJx+JBKxgeJGGfkEy7LQ\n3d1tEy2RQ7AsC7FYDA8//DD27duHxcVFAMDKygquXr0qKULdqIal2ARMoEVMchFqApdeIMMYAqMW\nguk0tx5DzZGEQiFpg8+NgPOR84A8A0Flfn4e2WwWyWRSBFVbbV97YDh58qScB0H58dWrV21dmrmj\nAK2JEAwGMTQ0hJWVFdmN6ZozbmTszlibuxwnkpYdU2qrD5Zhmow7Rb1el0NpdXqOOwx/ZtZDx7Da\ns2HFJ58LtICir68PqVRKDuRdWVn5RM0Gy4s5ud999115X51iu3jxosiWN1oxqfP8o6OjOHbsmPTg\n1HUPBCaej/H8889jcnJS5MUM8wh+uitXIBCQdCdjfy1a4vfn73r3J2hx3nDDYEjH8dKgTV6CcyYc\nDiOfz8v993g8spEsLy9jamoK+/fvh9frxbPPPotf/vKXGzrGn2Vfe2DQuelYLCaqwk9ipsnWLy0t\nYffu3ZLnJknIMABoaw9IWjH+5GLkrsbFxF4P3CkIKJx0WsrMXUWfK6lDAk5uSmrpRfAaCSScdLyO\nDz/8ELlcTprFMF3HVC2ZeP0aAgI/jzzJ/Pz8ujBko433p1ZrnXHJQ3B4rfS6KpUKLly4gA8//FBA\nkrE/MwPctZl1IMhwwXNxay6JQKHJYU006swEAVv36QDaIKOzSyzsIpeh5xJTl7Ozs8jlckJEb7V9\n7TkG1ukDrVORpqenUSgUbGkqfaP5r1Qqwev1imvNhaLTUkD7ZCOSjJxoXNzMVpBwIihw8WptBd+T\nWgZNanHycFJTGhyJRGyCJcazuvajM56lx6NDILfbjXw+b1NcAu2CI4IFLZvNijpwozMTBCISjslk\nEo1GA9FoFMlkUsaqUChgYmIC77zzDt577z0BBI6vx9PqJ9nf3y+Lk6/VtRHklDgOAGR8tW6F90mP\nja5JYfjAEIFen5ZB6/QqwZZdpRgaWlZLrr+wsIBcLidCuK20r73HkEgkUCgUUCgUMDs7i4sXL0qK\n0Ov1Sg9ELmq/349qtYrl5WV0dXXZFhYJO71z0POge8oJwPMpKEbSPIbmB9i3gaSjZVlSE0CPhWEK\n0K4I1IfOMLblLkVjuTC1/nyMoYsxBouLi9I6bWFhAYcOHRJA5ETXRUlAi3c4f/687Kocn40ycjf0\nmsbGxjA3Nyddpzim6XQa//Iv/yKksl6EHAuCIA8C4lgSJHjPmHUgcPr9fiQSCSwvL69LWwPtcIfh\nJecDwZeeG1WiBC3tkWgvkfeG/BK9TAAbnvn5PPa1BwY9yfP5vDRyJeHECQW0q94sy5LDQbQkl5OM\nRTj8uVOZSBCgN0CdAz+HAh0tldXnO9L7YLqscxLpMEO78UxzcqJqtzsUCmFwcBDFYhHLy8syQelp\nlEolUXtq3QaNIQz/Ro1BKBTalNZwOnvD70j+hvoEHlyrQyutCeD30vJoypa9Xq+EI6zTYGjFBUxl\nrA4hOT8AyALWj9F70kQ17x3Bg8Z7TQ9Ucz3s2wHAtjFslX3tQwkuVJYe5/N5GwGo+QagLU4hiUey\nizefO40+Y4DvRbDQ/QX1ZOBr9ZkSmrzUhBVdUrr6lOPyOwFtr4RuKBcIiU16Qm63G08++SS+853v\n4Bvf+IZtIusMAMEvGAzisccew2OPPSZgwAX36KOPAmjVdcTjcSkz3kh75ZVXZFFxZ+Z9IBDT6+ok\neQkkVC9SuciMDd9Hl8hruTh5C904RffOoCdAUCDYUDhHUOH7a8k87yM/gxwK30dfz/LyslSOMmux\nlfa1BwYAsosuLCwIEJBUYx9GoH0svWagm82myJdJYupKxE4JbqPRkEIqnhrNsIAlzxpYtLxWhwKM\ncV0ul0icE4mEcBVer1fIOIYcrEykS0zZdCQSkXMzlpeXceLECfT29sqk5AKju3vw4EG8+eabci26\nfuCtt97CxMQEfuu3fmtTwggax4IS7507d0p2ibsrPSrt9fEe8LVczAzn9GKlcpXEJDcIeiocawAC\n0uRz9HvpNCrnjxa1AbClQZm6DoVCAlS8Tmpg2AdEi9q20r72oQRjvHA4LClHfcO4W+obTWUj0Lqh\nBw8ehNfrxdzcnCC+jmk5wThZGQezFyPJJmYvGMowNOHuQ9UkYC97JhFqWZZwBp27ZigUkpJqANIY\nliKhn//854hGowgEAnjooYek5VupVJJcfiQSQbPZxIEDB3Dp0iUALT7h7bfftgmkjh07JnyL1+vd\ntFQaiTru2oFAAOl0WsDV62219tcEsPbCGo2GFKrRK9DFVfT2dMGTDtmYueAY855rwZi+Vn4Gs1ud\nKVMCB78XNxeGpAQOvrduMLPV9rUHBh1vU61I3oELiuy/2+2WRZJKpaRJSbFYxMDAACKRCKamppDL\n5WwCKd5I8gR6EREU8vm8XAe9ESot+XMng53P523xJ9B2e/naZDKJZrOJY8eOYXV1Fa+++ip6e3tx\n8OBBlEolDAwM4J133pFUZK1Ww9zcnC3FypBjZGQEPp8PQ0ND+IM/+AO89tpruHTpEh577DG89957\n6O/vx86dO/HAAw/Y6jc2w1588UU89dRT4sIbYzA4OIhKpYLV1VXhCBhacBGyiI0kHj04Eppc4Hyu\nJil1ab128Vlp2mi0eoRSEs1NRYcWBAvdrFenuAlGOpXNz2IqlZ/L4wY2OuvzeexrDwwMG7TyjAQe\nU39cjD6fD729vUgkEqjX69I4lZMqHA5L3p83i12cSTbSveexalS5hcNhSWGRm+AC52TkhOAOSK+C\noEOwoTezZ88eHD16FCsrK+jq6kI0GsWRI0cwOjqK6elpnDt3Dvv27ZPPpLvKrAzBhu/HNKnL5UJX\nVxd++7d/Gzt37kS5XMaZM2cQj8fR3d0tC7XRaGxKNycAePrpp0Wmzn979+5FNpvFzMyMLYbnTq55\nAx0a8f6yS5QGdXp7HBv+jV4dPT5daMV7RdEU5xY/h2PT6YHQtDCKv/O+6jJ7god+7VbZ1x4YNONP\ngolIrY+GZ5qQcl+eBMXHO2NR7tws0AFgy0RwkZPV3rlzJ2q1moANd/x4PG7rLAS0K/r4nuQo9MEq\nyWQS/f39iEQiiMViwkW43W68/fbbmJycxNDQEEKhkLRy07UZetJzTHROnjvYQw89ZEu7AW2w3aze\nhKdOnbJVH/JescEKW7WxeYzX6xXpMYFU34NOr0Znkqhl4PdPpVKwLEu8S4KPJiEZFpDnodeg+Sm+\nJ9D2Pnjv9LkjQDsFrUlOHbrcjZqJbQEMbMhJHkBLoIG2YjCdTtsERbrKUSsZjTGSAtWqNabHuBsw\nbVavt5qujo2NYWRkBNeuXcPKyoq4lmTD9UGtWkrL2JTPsSwLi4uLuHHjBk6fPo0TJ05IhuXXv/41\n8vk8hoeH0Wg0cOPGDZsak0DDWLleb53wzZiWu57mXXT1IetNNrOBCHUKmtgsFAr4h3/4BzSbTfT0\n9ODGjRvwer0YHR1FqVSSTkmJREJid6YfdbqS2g5mp/x+PyKRiICO1+sVaXo2m7WlqUkqMqXLcSJo\nai+hk4egR6P5LYahWvymPUVKp++Gfe2BgUhMsQgXmNb+04XUhTQEB436nSo37jzc/fk+mtnmbpLJ\nZHDhwgXRU/Bzs9msrWCKXgczF/xcXi8nDD2Wqakp7Nu3TwQxPKyWNQD0ivjdaVqUo1NpeiF4PJ67\n0guAmRZeG8MtCn2WlpbQbLZK1vv7+3Ht2jVZsEBbrUlPkSDHn0kuh8Nh7NixQyTXN27ckBCQhWda\n06Eb/pJ70B4KvRzNUzB9yg2KQqp4PI5ms2k7dpDXyLlA/mOja1E+j30mMBhjAgBeAeBfe/7/Y1nW\nnxljkgB+CmAUwA0A37Esa3XtNT8A8IcAGgD+V8uy/n1Trv5zGCcWG6XwZmoxE3/mAqdRxabdeIID\nuQXuTiQJuStwYuuu1FoyDbQXKsMNupA6Zx+JRLC4uCiLnIu22WxV812+fBmBQABdXV1YXV1FJBKR\nnYvpLwKgrvcgYOg0XbFYRC6XkxPACYp3y7iwbt68iZs3bwJod9g+cuQIjh8/jp6eHlGvEhABiAis\nVqtJiTTHhR2pqMNYWFjA0tKSrW0/d30tkCOfoGtJ6DHSE9BkMe815xm7eNVqNSmq4zjzZ01k9/b2\n3rWzRT+Px1ABcMayrLwxxgvgNWPM/wfg9wG8YFnWnxtj/hTAnwL4E2PMQQDfBXAIwCCA540xey3L\n2pyE92eYPv+RR53xcRJIRGveAJ1epJFcYpksMxp0+1iqHI/HMT4+jitXrkifRwIKF329XhcvgZOO\nAEb3udFo9SBkSzCdPmUbMIYDZ8+eFf3Ct771Lbz66qtShkxQ4/eim84W7F6vV8Q88/PzmJ6eRjKZ\nlBDmiSeewGuvvbYFd6plJ0+etC2EXC6H5eVlLC8viwcFQAjJqakp3Lx5E6VSCV1dXTh48CCSyaQ0\nwyF4azGSMQa5XA4LCwsS33M8mRngIgfalZJaJUpw0KpGeg26AIubhNfrxezsrIDt9evX5TVsa89N\niHORzXTuyayE1dre8mu/etf+WQB+F8Cptcd/AuBlAH+y9vg/W5ZVAXDdGDMJ4DiAtmJmC427NlG6\nM3et3TadC+fjzC/Ts9Dko1YiEvl5gvHExIRMSLq0JPV4XZqAIiNNsGDu3eVyyXWHQiGZNJo1J8jQ\n0xgfH8e5c+dQKpWwb98+RKNRnDt3Tsgt6iK0BoOu+vT0NA4dOgSgXeRz6tQpvPzyy1tyv7jT09Ni\nUx1yLtyNP/74Y6yurkr44/P5cOTIEezfvx+RSAQ7duxALpdDNpsVkMhkMnIfGRbocJLzQbfO40Jn\n6MaiOAKCbkhrTKvmRYd9AGw9JPi/JkQJViQ7OQ94b+5ZgZMxxg3gPQB7APwflmW9bYzpsyzr9tpT\n5gD0rf08BOAt9fKZtcc63/P7AL4PbO7RaFp+zF1XVzQCbdky3WwKi5hO5ETRZJhWz+m+fZlMBleu\nXLEJmzRRxc+le6k9Dqa9uLN3jJcQoQyFCGjs/uTxtHo47t+/H8lkEh999BEOHz6M69evo1KpSLGV\nz+eTDkyA/Xi4lZUVzM/PC3nJMdqK3oNPPfWUjBsXDrNETKPSha/X61heXrYVlTUaDTkHlP0fC4UC\nZmZmJJbXgNyZhWF2iGOhW/7rMec91LyFLkvvTKPqcFXPN3oM+v25IZF4JHhttX0uYFgLA44aYxIA\n/rsx5nDH3y1jzBdSuliW9WMAPwaASCSyadKuUqmERCIBt9stJbjMSXNhsI6CuzQVjJwkrIIkF0CZ\nKieIro1Ip9O4dOmSSHn5HoVCQY6L43WtjYMtV854n81OOWm4w3FCMlPA0utoNIqbN29iYWEB4XAY\nc3NzmJ2dxa1btyR+5nciGDHLoEOpYDCIixcvAgCGh4cFLDczzj19+rTtfrFXxPLyMm7evIl0Oo3u\n7m5UKhXpA6E7UnHxTUxMoLe3FwDw/vvvY25uTsCQYKPjfwCSvWDmxuVyyXzgexcKBSGaK5WKHObD\nOhXeBxZlERDIGel0sPZYCVKci9yQKpWKHNEHYN0msRX2hXwUy7LSxpiXADwLYN4YM2BZ1m1jzACA\nhbWnzQIYUS8bXnvsrlg+n5fzECzLkvSPro8gyah3BKBdIxCNRkVtR5dd31zG6VxgWl3Hmw205NkM\naZjBoBei05KayNKkJRe1bngai8UkNOBhNcYYrK6uSqMPfl+Co245Ry9ENxzx+/1YXV1FKpWS9J8x\nBk888QSMMRsqajpz5oxcn+50RML49u3biEQiePTRR5HP5/Hqq69KWpmZHxY9zc/P49VXX0WpVEIm\nk7FlA+iaU7WoPTctiuI8oKfARUslJceeNSiseQGAW7duyTiT26IXwrnF76oBilkm8k3BYBD33Xef\nbU5utX2erEQPgNoaKAQBPAPgLwD8HMD3APz52v8/W3vJzwH8kzHmv6JFPo4BeGcTrv1zGZuJkOnt\n7u6W7AHQPuOx00sA2p2YKU3VuwHQLodlbE+REScbU15c8OQsNHAAkNOgSAByYXBX09wEJ9Pw8DD8\nfj/S6TQqlQpSqZRMJu7yzK/Tw2FxF8GAIEOOguHQ8vIyzp8/j1AoJOIpr9eLfD6/4W6tblrCcbWs\nVt3IysoKvN5WS3dmV7ibcxz4nfL5vBwLwJ2cWggChP4crWXRoZ0ee4KPBhKCkdvtxo4dO9DV1YX5\n+XnMzMzImDYaDWn9T7KSAMBskQ5dNXA0Gq2GNLt375ZrvSfJRwADAH6yxjO4ADxnWda/GWPeBPCc\nMeYPAUwB+A4AWJZ12RjzHIArAOoA/uhuZSSAFvHDWNTn82FgYACxWAyZTGbdAmf8TU+Aj+kO0Jwo\nWmqtq/noEdBTYI1EOBy2lURzspHHIMdA6TSbp5CIpCeh+wXQVe7r6xOxD88m0O3DWAxEebdWfHLy\n8dQnlo4vLS3hxRdfRDQaxdDQkLjbdxJSPP300zbpMrkZLkCmTC9duoTbt28jnU5jaWkJN27cwJtv\nvimZF3pydO+Xl5exZ88epNNpLC4uirelxURc9OQDSCpr8RbQLvPmou4sugIgkvhqtYpLly5Jw1bt\n7VEXo+XjeoPgZ/Pz6G0CwL59+9DT0yP37p13tn5f/TxZiQsAjn3C48sAnvqU1/wIwI/u+Oo2wF59\n9VU8/fTTACBFRz09PchmswgGg7KbcIfQHXg4gSlcocunySctgWY1HxWT9FL0jqQnJNCeTHwfAFL8\nw52GE4eApcu6Y7GYnCdRLBYxMTGBy5cvS18FpkA5wfn5oVBIPA6g3QSXHg7Tp2+99RYef/xxdHV1\nyWT/onb8+HEBQB1383vV63VkMhnk83mk02msrq6KB8DrZwxO1h4AkskkZmdnJSXL/gU6TNPyby10\nYtNbgjvnATt4aU5HE4cEtnA4jMXFRWQyGZuXxr4P9Mp0Q57Oug7dy5OZDLe7dfAPS+43q5/mZ9nX\nXs/cNYQAACAASURBVPkIQIhDoAUOw8PD+Pjjj2WhsKswAElt6pSldp+7u7uxtLQkKSW66CyU6unp\nkUIrl8uFfD4vrDirN3W6iru3Lu7p7e3FysqKuLWlUknCFV4PW7/z2mq1Gm7cuIHLly9LWo6TC2jr\nH+r1OsLhMLq6upDJZIQUoypPF3a5XC7Mzs7ijTfewP33349UKvWlMkidaT+Xq9UrgjUY1CpUq1Xk\n83nbga7hcNhWL6DdawJxKBQS0o6cDK9T61Q0p8BFr7mmRqNhkzdrIpqeI+9PrVaT8SM5HAgEEIlE\nbOpXluHz82j8XC27r9frGBkZwX333Scl8P/xH//xhcd7I2xbAIOWGBtjsHv3brz88svrdhXeSObM\ntdZBZwq4o7C/wcjICGZnZzE/P49cLicLOh6PC29B9CdRSGKRWgjuiKlUCuPj47h69SoWFxclDNEp\nVKbhGo0GHnjgAVy4cAGXLl1Cb2+vLbMCQArAwuEwgsGg8CWrq6si/3W73chkMuJ+02NgL4Pp6Wkk\nEgn09fV9qVOY+R3J2mcyGVlYPIWLmZJCoYBsNiu7b7PZFG+FQEiytFKpIJlMoq+vT2J5hgm8j16v\nVzwJALbdn+BMYOdC5/enl6bbwblcLiwtLdmAhtyBroqll8N0KADhd+g96nMomNl65JFHsG/fPpRK\npbvSHZq2LYABgE2oFAgERPnXKVTRTVYZj9KFX15elknDaj+v14v+/n5MT0/LgtN5eJ2C1DJkLgQS\nZJxotVoNy8vLUjWoAQWAbaJbloW3335bTnPO5/M2FR3DJXo1/f39mJiYkO9N9pyuOcGAHhaPl+ei\nIIfyRY1eCMOA1dVV4QO4oxOw2GOB6kJ9crhm6Qmq5E1GR0fFS2CakXUJdNP1YqXXxu/J70pCkuOr\n+2N0Zqv0+5Ar0HyUJj41gcnXdmYn/H4/9uzZIw1oeLjw3bBt0drtzTffXFcEMzAwIKQXJ6AWngDt\nNmE6x83dimQe241p1xVotybj+YPMu2tCjDUOfD1dblZf8ig8hhm8DmYSmC4zptXXMJ1O29KmtVoN\n2WwWtVrr2LpQKISenh7ZiVmPQTeZKUN+f3o6sVgMg4ODNmn2FzF6MT6fD4uLi7h58yampqawuLgo\ncme60+x9wZ2XSkiOPdl89nEkkFYqFTz44IPSbZu7NwGf94/3h4/RW+R31Z6BXuhc+OQ9tHiJz9UK\nRv7MDUbPI4IJeQkCQyQSwZ49e6R/5F/8xV984bHeKNsWwABA8tB0RY8cOSLxvl6selHoohq65sxj\ncycvFouYnZ2VXg1s0kJBEXc86udZ58Cbz8+gi1ksFjE3N4dGoyGgolNlOo7WOXASbnTTfT6fHPqq\nd+qhoSHJkNAzoKfARaV7L+zYsQOnT5/Gjh074HK5vtQupouXyuWyHAtPT6her0uHKb/fLyrHRqMh\nYQUfAyC1B/F4XB4rlUo4ceIEHn/8cfGq2LwGaBdf8WdeU09PD8LhsI07IQARPPU9Z/8GrW7k81lT\nQaDOZrO2ak39T4cbBKORkRHs3r1bqm/vpm0bYHj99dfR3d0ti6KnpweJRELYce1O61QiAFtMymwB\nd7FcLodr167JxKY7yphXk1eMp7ULyt2Ri4afR7ELQalTjAO0BVN6YrpcLqky1OckcGcF2rGu3pm5\nexHQwuEwEokEHnjgAaRSKTSbTUQiEfT19eGLGvtOEqhIFOowizUIBHACKgGCuz2//9jYGA4cOCDA\nODU1hatXrwKAlDTzPtIb0SlBcgM8+Jb3l+49MxkEb6pQGSLw+QA+8eAfpp55mAzDz84whj8Hg0Ec\nOHBAukPfjUNmtG0bjgEAUqkUSqUSbt26JSrAxcVFIQO1dp7nVlIOrfs3cOLwNVrdpivxmDFg5kO3\nAWNIQlcZgFTW6fZhnMyc2ADkLAROuFwut45B17suF1s2mxVCUysMeWKWbhzj9XrR19eHoaEh0Tn0\n9vbib/7mb77wuDNc0YIprRPQVY0cM3pBQLuYiyFfNBrFoUOHkMlk5FQxy7Jw9uxZ8TioJWHGSZ8d\nAbSFYvwsLZHXAEygJ1gB7WPnAEhNA0/X5mPMlACwaS9cLpftACIN6gcPHhS16k9/+tMvPM4badsK\nGPr6+pDJZJBKpfDOO++gv78fly5dskledRMU7uicEGyPpglK3lzu7jodxpvMScZybZJ+fX19Nlk0\n6yi4KLTnQWKUOgAdbxMUTpw4gbNnz8rEZDUm37NarWJpaQnj4+NYWVmRxrbcBdkIheKjRx55RHbz\nwcFB/O3f/u2XGnc2UanVasKdcIEA7awFv7MuXtKKRIaCuVwO169fRzqdtvXPzOfzUgejU4RcmAQ+\nTRjqYwDoEQSDQTmFrFgsyn1mRkqTy7xWahJ0tafmNEiIajKb19JsNnH06FF861vfwvnz5+96GAFs\nM2AIh8NYWloS8nFpacnWXpyuPnd9utm6pwEnELkKr9crsTl3fLq8JDQZPjDH7Xa3Dlrt6urC1NSU\nTfDjdrdOb240GrauUxRL8Zq4A5NPaDabuHr1qg2g9ERk9qFYLApJqXP1nKT0noaGhiSG7+7uxt/9\n3d99qTE/fPiwcCfcweld6VQuwyD+rhcNYD9xulKpSA8GLjK94LR2A4B4TQBsi47jBLQXOEPIXbt2\nYWhoCLOzs7h27ZpI1bUcm+EdAUM3WtF1LyR5eQaqBibLstDd3Y2jR4+iv78fc3Nzd6XMutPu/hVs\nof3gBz/AH//xH2NiYgLf+c53UCgUsHfvXly8eFFIIO22cxI1Gg0R5Ghlo+66zImid3TdhIWAA7Ri\n4AMHDgivQDKKOxw1BlpiC7R7SzDmJhBRmAS0BTPau+FiokcyPz+PxcVFETtxAdHDSCaT2L9/P3w+\nH/r6+my8xhe1UChkEzYxN+92u236Arai0wuO35f3RIdFFIwRyLSnwXHgvaOIqzNlqJuv6lL8QqGA\nq1evYmVlBXNzc1hYWLB5L+Qe+HztFWolJa+f0nZmxTo9ob179+L48eNYWVlBOp3est4X/5ltG/KR\nRpfW6/Xi6NGjGBkZsU0e3mjG/XonDQQCwidwgeo4UmcfwuGwFNLoeLXRaGB0dBR9fX1CTnLXYXjA\nCURXlJwAxU16ctNVJgfCiUjvhMw6PR9+HnUYvCbNeRw4cEDO1wgGg/inf/qnLz3efX19NtDkWHDx\n83GOhfYKdDZDh2jaEwqFQrjvvvuQSCRsPTJJFvLMUIJHIBAQGTlVpCT/tNcyNzeHDz74QM6v1LwI\nABv/QY8HgGgx9PdgiKNBjpsOlbi9vb2Yn5+/KwVTn2TbymMA2gzy7OwsDh48iF27dglYAO3Tohir\nalm0ltdSMKUXsO51QA+EC5oTwe12Y2BgQPo/cGHrikhep9ZGcIFrubLuD8EF1tlDkJ9JHsTv90th\nF4lQnfEIBALo7e0VcpbhzJe1RCKBqakpGTdWIWrREoGa403ilCESAAnBCLzc6cvlstRL8HsQIDl2\nHH/u8gRCelmflPXhz9rTIBjRGNLx/nAu0IsjkBDktAqS10Hhmc/nw82bN/GrX/3qjsZ7o2zbeQx/\n9md/hu7ubnzwwQdIpVI4fvw4RkdHAbQ7SufzeYkLGTro3YJEYDKZlL58OiamS8wJqM9I2LdvH65f\nv44XX3xR9AI6jcl+jEA7K6EJNM0fAO0Fw9x5sVhEJpOR/H+pVJJzLMrlMhYWFoRf6AQjr9eLRCKB\n7u5upFIpRKNRPPfcc3c03qzDIKhdvXpVzoXg7gm0CUigRdRRV6E5Bi5QWq1Wkw5PFEbpdKMmHLnD\n0yNjiKXfjx6F7mHB+6qzThrUeO/dbjd2794tylO+B8GasnZ6RQSR4eFhaeTLvqH3gm07YACArq4u\nib937NiB4eFhcce1m65rEoDWDsE0lGVZ6O3tlV2Fk5IkJJnqUCiEeDyOrq4ujI6OwuPxYGJiAouL\ni0in00ilUjYVHXc87qC5XE4+V0uTqX5k6ksrFqnLoNcQDoeFvedzNYNON5veDOsPvkxdRKcRYN1u\nt3g33GW1HFx7R4lEAuFwWA4c5gKlBwZAPDj+zoXG+0QwYLhE74rP1XyDTid2pjEpSNJ9GPUmwLnB\njA9Vpbw2/dxIJCJeCu9xb28vms2mCNPuFdt2oQQAKTdeXV3F3r17MTw8jFQqhdnZWZm0+gYy1ubR\ndeQA0um0FN7E43GEQiFJ+fF9tCsZCASQy+VQLBZhjEE2m5UzMjOZjCwUcgGcdKym7CQjGQroClAC\niI6BqYrkYikUCraMAHdjv98v1aGNRkN29jsxekqUZWu9BXdX7sjaC+I4ay+Jz9F6Ed1tmwta10Z8\nEghoGTI9h87PAGAjb3kfdKNYAhE5KB5iw8/i9WuvhHOrWq0iFouhr6/Pxm/dK7YtgeGHP/whvv3t\nb+PChQvYsWMHenp6MDw8LPEvYz824wyHw8hkMlhZWRH5bK1Ww+3bt2Wn52JjLMsFrLmG1dVVZDIZ\n2+LPZrPiwWjCk+4+JwsnKDMSAGyTkDyDx+NBLBYTEZTP50M+n7cdbKPrHbgILMvCyMgIhoaGEAgE\nUCgU8LOf/Qx3asViEdFoVE65otiL4MieEXpxZDIZAPjE1Cu/I0O0zh4ZWn3K9KwGA35Xfne2feOi\nJn9BMKUAjdfOTYHzRAuX9D3Sre51ipMg6Ha7sW/fPgwMDABo9Qr9+7//+zse742ybQkMQEtMlE6n\ncf36dezYsQMjIyN47733ZBJwRyJZt7KyIm6hzlzwdx076l1Hcw06v00Sit2jeGCK3okAO3FojJHY\nf2lpCfl8XkCMz9N6Cu7SZOiZsuRk53FzbE4yODiIRCJhS9XeqXFXn5ubAwCMjIxI1Sevk9fPhUhP\nhsDHRqs6qwLYFYo6fteZJC5GhgG8DwQbhiDkFjRHxDQmVaY65COIEXD0fdPXDkBIUoZ7brcbfX19\n2LNnj3gPGxG2baRtS44BgGj+b926JWFCMpmUxcvdhseeczJowowTmqZ3dMa3/LvWMXD3o2DJ4/HY\nQgBOYlZdcgF7PB4cO3YMDzzwgGRF+LkEq07VJndAEqnczZj1IMEXi8XQ399vKxbaKNOLdf/+/aKd\n0GXwPI1bLyh6DMlkUv5Ocpa1FUC7JZ+WkpP70QCns0Rc1OwcxXukOybRa9Cdqzo9Bc4DTXhqEZPW\nOGi17NjYGGKxmGg57pTk3WjbtsDw13/91+ju7hZdQiQSEVbZ4/HILsVmGpx02o1nzEqAYFzJhR6N\nRmVyA5DYOBKJSIeeWq0mp00xxOCkJT/h9XqRSqXQ1dUli0qn9LQOgouNKctarWbrvMRrZBETZdo7\nd+5ELBZDLpdDf3//hrm1//iP/yg7st/vx+joKB577DGpJ6F0vF6vy+InOBOgcrmc7URx3gd6dTqN\nqFO/HA+CBH9mly4tVtJNewgQJAyZVWFlJUMN/tMKUoI1U5PGGMTjcfT09MCYlry9u7sbo6OjwqUw\nC3Uv2bYNJYA260xVY3d3NwKBABYWFoQf4ELTYQD/5yIG2sfZcUI3m00bYah1B9zJo9GoTYqriUDu\nPFrV12g05EQpxsRUV3ISagKOk5YLj54I9RNcQEBLjckJr0OZjTDdrRpoeWs8EIYLiQucDXT4vehm\na0IRgBC93L1J7lIE1hmyaTKyM92o/9ceAe+jZVnCiejwgZ+pdRAaNHhf+D2pnD106JDwPJFIBL/4\nxS82dLw3wratxwAAf/VXfwWgfQxaPB7HyMiI9GkA2qdca7ELQYGLmJOW8X2lUhGJL18HtFNsjUar\ntyDjTp0dYKxMkpBeBxV1PGpNV/xpFp2cARdIoVAQ7oLXoI/O4/fz+XxIJpOIRqP44Q9/uKHjzHGL\nx+OwrFZDEqoPdeaF4+bz+WScuRtrgpLeDvkAArROi3JseI90daQGRnoAACRdqNO6JEi5AWglKhWm\n0Wh0XQhBbocNdFiMNTo6il27dq3rRn6v2bYGBqBNFLEC8ODBg7jvvvtkAtAT0K3LOfEASLMWHWPS\nG9Cehi615a7DiU4VJNAWNYVCIfEIcrmcLHDLsqTMmhOQbjFrIWq1muxSneo7ehGs/uPzS6USdu7c\nKYfzbKQ999xzsiDYZ4G9KOnKl8tl+Z4EB45ZZ1pQ8yusImVvBZ66xXDA5/NhaGjIJo3mfadCkeMK\nwOZZ6aPrdIaJ94ynUo2NjWH37t1Cdmo9iy4B379/P77xjW/IyVShUAhvvnlXjnT9TNv2wPCXf/mX\niMViMjkCgQDuv/9+OSKME1DvuExrkV/QvRyZHSBY6PMagBbPoJWONHIJfD/umAQoPk6WnmBDMOLp\nSwQoejD0QMhfAO1CK4YxXq9XOjOx49FGW3d3N/L5PLq6uuDxeATEgHbYQ36B48X7oVl+rSGgi89m\nKgzVtJjKsizcunVLZOAkFzWHwdcwM9EpoqJeRJ9kzXt969YtfPjhh9IgltfFXpvMKCWTSRw+fFg2\nm04V571m25pjoFmWhVgsJjcxEAjg4MGDmJiYwMrKikw6ra/vFKWQF9DaeT5PH8hKQOHftHQ2EonY\nyrqbzeYnpjDJbutmrVq2S5JMT3xNarIAjNfV29uLw4cPY35+ftM6EzN8CofDSKVSovisVqtyxkU2\nmxVylKBF0lLXqwDtVCV3d7fbLVwKwZD3SnMDBAugHVLoVC9FV5q8jcVitsNxKHHntXSmSWm6IOq+\n++6TSlXOlXuhivLTzAEGtJjzp556yqae6+3tRX9/P7LZLC5fvoyFhQX5O9OBnVqFThHOJ6WtdB9J\nsuOaKOSkZLfkSCQinYEILPQmyGNo5SK7PAOwLSIesEtOQbPoR48exdDQEKampkS5udHGE7f9fj8O\nHTokYrFcLicl5jrW101utWuvuzwRiDu9AJ6RwR1ci5uAdqt+ytvZzq7RaNjCCoaPiURCCGrefy5w\nXgvDOWZFNK/z8MMP4/Dhw7aU9SuvvLIp47xRdu/6MltsL7zwgixqxrcuV6v56c6dOyW9yEWrJxCB\ngO6rdmW12g+AkJXMfeuS6EKhgHw+L6k5LgJdAKRJTu1+c8Kxq3SnFJehh9frFZISAHbt2oUTJ07Y\njsHbDPvpT38qDVJDoRBOnDiBgYEB2bEZ2vCa9XF4XLzMVGgNA7048j6fpCVhpoUcgC5uI+DwHvL+\ndJKJAGRcOZ7aa9SZJHotQCsD8/+3d7axUV5XAn4OE/DXjLHHH8RfGAcSAzEEEkAkjih22U0pZLNS\nqqaqdptWkfIn0nYVrSqqSqvdH1GbrLRt//QHYreNlE1oKtp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      "text/plain": [
       "<matplotlib.figure.Figure at 0x129ebd0f0>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "#Visualize prediction mask\n",
    "\n",
    "index=47\n",
    "print(\"Predicted\")\n",
    "plt.imshow(imgs_mask_test[index,0], cmap=\"gray\")\n",
    "plt.show()\n",
    "print(\"Ground Truth\")\n",
    "plt.imshow(maskstest[index,0],cmap=\"gray\")\n",
    "plt.show()\n",
    "print(\"Image\")\n",
    "plt.imshow(imagestest[index,0], cmap=\"gray\")\n",
    "plt.show()"
   ]
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "Python 3",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.6.1"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 2
}
